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G-quadruplex DNA and ligand interaction in living cells using NMR spectroscopy

Gathering structural information from biologically relevant molecules inside living cells has always been a challenging task. In this work, we have used multidimensional NMR spectroscopy to probe DNA G-quadruplexes inside living Xenopus laevis oocytes. Some of these structures can be found in key re...

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Bibliografiske detaljer
Udgivet i:Chem Sci
Main Authors: Salgado, Gilmar F., Cazenave, Christian, Kerkour, Abdelaziz, Mergny, Jean-Louis
Format: Artigo
Sprog:Inglês
Udgivet: Royal Society of Chemistry 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5490339/
https://ncbi.nlm.nih.gov/pubmed/28706695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4sc03853c
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