טוען...
Artemis-independent functions of DNA-dependent protein kinase in Ig heavy chain class switch recombination and development
Assembly of Ig genes in B lineage cells involves two distinct DNA rearrangements. In early B cell development, site-specific double strand breaks (DSBs) at germ-line V, D, and J gene segments are joined via nonhomologous end-joining (NHEJ) to form variable region exons. Activated mature B cells can...
שמור ב:
| Main Authors: | , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
National Academy of Sciences
2005
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC548986/ https://ncbi.nlm.nih.gov/pubmed/15699324 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409857102 |
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