Novel molecular subgroups for clinical classification and outcome prediction in childhood medulloblastoma: a cohort study

BACKGROUND: International consensus recognises four medulloblastoma molecular subgroups: WNT (MB(WNT)), SHH (MB(SHH)), group 3 (MB(Grp3)), and group 4 (MB(Grp4)), each defined by their characteristic genome-wide transcriptomic and DNA methylomic profiles. These subgroups have distinct clinicopatholo...

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Bibliografiske detaljer
Udgivet i:Lancet Oncol
Main Authors: Schwalbe, Edward C, Lindsey, Janet C, Nakjang, Sirintra, Crosier, Stephen, Smith, Amanda J, Hicks, Debbie, Rafiee, Gholamreza, Hill, Rebecca M, Iliasova, Alice, Stone, Thomas, Pizer, Barry, Michalski, Antony, Joshi, Abhijit, Wharton, Stephen B, Jacques, Thomas S, Bailey, Simon, Williamson, Daniel, Clifford, Steven C
Format: Artigo
Sprog:Inglês
Udgivet: Lancet Pub. Group 2017
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5489698/
https://ncbi.nlm.nih.gov/pubmed/28545823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1470-2045(17)30243-7
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