MEDU-06. NOVEL MOLECULAR SUBGROUPS IMPROVE CLINICAL CLASSIFICATION AND OUTCOME PREDICTION FOR CHILDHOOD MEDULLOBLASTOMA

BACKGROUND: International consensus recognises four medulloblastoma molecular subgroups - WNT (MBWNT), SHH (MBSHH), Group 3 (MBGrp3) and Group 4 (MBGrp4) - each defined by their characteristic genome-wide transcriptomic and DNA methylomic profiles. Subgroups harbor distinct clinico-pathological and...

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Pubblicato in:Neuro Oncol
Autori principali: Schwalbe, Edward, Lindsey, Janet, Nakjang, Sirintra, Crosier, Stephen, Smith, Amanda, Hicks, Debbie, Rafiee, Gholamreza, Hill, Rebecca, Iliasova, Alice, Stone, Thomas, Pizer, Barry, Michalski, Anthony, Joshi, Abhijit, Robson, Keith, Wharton, Stephen, Jacques, Thomas, Bailey, Simon, Williamson, Daniel, Clifford, Steven
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5475124/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox083.157
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