Novel molecular subgroups for clinical classification and outcome prediction in childhood medulloblastoma: a cohort study

BACKGROUND: International consensus recognises four medulloblastoma molecular subgroups: WNT (MB(WNT)), SHH (MB(SHH)), group 3 (MB(Grp3)), and group 4 (MB(Grp4)), each defined by their characteristic genome-wide transcriptomic and DNA methylomic profiles. These subgroups have distinct clinicopatholo...

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Dades bibliogràfiques
Publicat a:Lancet Oncol
Autors principals: Schwalbe, Edward C, Lindsey, Janet C, Nakjang, Sirintra, Crosier, Stephen, Smith, Amanda J, Hicks, Debbie, Rafiee, Gholamreza, Hill, Rebecca M, Iliasova, Alice, Stone, Thomas, Pizer, Barry, Michalski, Antony, Joshi, Abhijit, Wharton, Stephen B, Jacques, Thomas S, Bailey, Simon, Williamson, Daniel, Clifford, Steven C
Format: Artigo
Idioma:Inglês
Publicat: Lancet Pub. Group 2017
Matèries:
Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5489698/
https://ncbi.nlm.nih.gov/pubmed/28545823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1470-2045(17)30243-7
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