Novel molecular subgroups for clinical classification and outcome prediction in childhood medulloblastoma: a cohort study

BACKGROUND: International consensus recognises four medulloblastoma molecular subgroups: WNT (MB(WNT)), SHH (MB(SHH)), group 3 (MB(Grp3)), and group 4 (MB(Grp4)), each defined by their characteristic genome-wide transcriptomic and DNA methylomic profiles. These subgroups have distinct clinicopatholo...

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Pubblicato in:Lancet Oncol
Autori principali: Schwalbe, Edward C, Lindsey, Janet C, Nakjang, Sirintra, Crosier, Stephen, Smith, Amanda J, Hicks, Debbie, Rafiee, Gholamreza, Hill, Rebecca M, Iliasova, Alice, Stone, Thomas, Pizer, Barry, Michalski, Antony, Joshi, Abhijit, Wharton, Stephen B, Jacques, Thomas S, Bailey, Simon, Williamson, Daniel, Clifford, Steven C
Natura: Artigo
Lingua:Inglês
Pubblicazione: Lancet Pub. Group 2017
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5489698/
https://ncbi.nlm.nih.gov/pubmed/28545823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1470-2045(17)30243-7
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