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The human immunodeficiency virus type 2 vpr gene is essential for productive infection of human macrophages.

The human immunodeficiency virus (HIV) genetic determinant(s) responsible for tropism in human T cells or macrophages are not well defined. We studied the role of the HIV type 2 (HIV-2) nef and vpr genes in viral tropism. HIV-2 mutants, lacking either vpr or nef genes, or both vpr and nef, were obta...

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Bibliografiske detaljer
Main Authors: Hattori, N, Michaels, F, Fargnoli, K, Marcon, L, Gallo, R C, Franchini, G
Format: Artigo
Sprog:Inglês
Udgivet: 1990
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC54896/
https://ncbi.nlm.nih.gov/pubmed/2236020
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