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Human Immunodeficiency Virus Type 1 Vpr Is a Positive Regulator of  Viral Transcription and Infectivity in Primary Human Macrophages

It is currently well established that HIV-1 Vpr augments viral replication in primary human macrophages. In its virion-associated form, Vpr has been suggested to aid efficient translocation of the proviral DNA into the cell nucleus. Although Vpr growth-arrests dividing T cells, the relevance of this...

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Detalhes bibliográficos
Main Authors: Subbramanian, Ramu A., Kessous-Elbaz, Allegria, Lodge, Robert, Forget, Janique, Yao, Xiao-Jian, Bergeron, Dominique, Cohen, Eric A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212198/
https://ncbi.nlm.nih.gov/pubmed/9529326
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