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Xenopus polo-like kinase Plx1 regulates XErp1, a novel inhibitor of APC/C activity

Metaphase-to-anaphase transition is a fundamental step in cell cycle progression where duplicated sister-chromatids segregate to the future daughter cells. The anaphase-promoting complex/cyclosome (APC/C) is a highly regulated ubiquitin-ligase that triggers anaphase onset and mitotic exit by targeti...

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Autori principali: Schmidt, Andreas, Duncan, Peter I., Rauh, Nadine R., Sauer, Guido, Fry, Andrew M., Nigg, Erich A., Mayer, Thomas U.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC548950/
https://ncbi.nlm.nih.gov/pubmed/15713843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.320705
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