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Co-localization of a CD1d-binding Glycolipid with an Adenovirus-based Malaria Vaccine for a Potent Adjuvant Effect
A CD1d-binding, invariant (i) natural killer T (NKT)-cell stimulatory glycolipid, α-Galactosylceramide (αGalCer), has been shown to act as an adjuvant. We previously identified a fluorinated phenyl ring-modified αGalCer analog, 7DW8-5, displaying a higher binding activity to CD1d molecule and more p...
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| Veröffentlicht in: | Vaccine |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5489412/ https://ncbi.nlm.nih.gov/pubmed/28483194 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2017.04.077 |
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