A Glycolipid Adjuvant, 7DW8-5, Enhances CD8+ T Cell Responses Induced by an Adenovirus-Vectored Malaria Vaccine in Non-Human Primates

A key strategy to a successful vaccine against malaria is to identify and develop new adjuvants that can enhance T-cell responses and improve protective immunity. Upon co-administration with a rodent malaria vaccine in mice, 7DW8-5, a recently identified novel analog of α-galactosylceramide (α-GalCe...

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Main Authors: Padte, Neal N., Boente-Carrera, Mar, Andrews, Chasity D., McManus, Jenny, Grasperge, Brooke F., Gettie, Agegnehu, Coelho-dos-Reis, Jordana G., Li, Xiangming, Wu, Douglass, Bruder, Joseph T., Sedegah, Martha, Patterson, Noelle, Richie, Thomas L., Wong, Chi-Huey, Ho, David D., Vasan, Sandhya, Tsuji, Moriya
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3808339/
https://ncbi.nlm.nih.gov/pubmed/24205224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0078407
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