Design of a potent CD1d-binding NKT cell ligand as a vaccine adjuvant

The glycolipid α-galactosylceramide (α-GalCer) has been shown to bind CD1d molecules to activate invariant natural killer T (iNKT) cells, and subsequently induce activation of various immune-competent cells, including dendritic cells, thereby providing a significant adjuvant effect for various vacci...

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Detalhes bibliográficos
Main Authors: Li, Xiangming, Fujio, Masakazu, Imamura, Masakazu, Wu, Douglass, Vasan, Sandhya, Wong, Chi-Huey, Ho, David D., Tsuji, Moriya
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919905/
https://ncbi.nlm.nih.gov/pubmed/20616071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1006662107
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