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Design of a potent CD1d-binding NKT cell ligand as a vaccine adjuvant
The glycolipid α-galactosylceramide (α-GalCer) has been shown to bind CD1d molecules to activate invariant natural killer T (iNKT) cells, and subsequently induce activation of various immune-competent cells, including dendritic cells, thereby providing a significant adjuvant effect for various vacci...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2919905/ https://ncbi.nlm.nih.gov/pubmed/20616071 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1006662107 |
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