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Structural Evaluation of Potent NKT-cell Agonists: Implications for Design of Novel Stimulatory Ligands
Natural Killer T (NKT) cells are a subset of T cells that are activated by CD1d-glycolipid complexes through a semi-invariant αβ T cell receptor (NKT TCR). Upon activation, NKT cells secrete regulatory cytokines that are implicated in T helper cell responses. α-Galactosylceramide (α-GalCer) is a pot...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2792987/ https://ncbi.nlm.nih.gov/pubmed/19732779 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.08.061 |
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