Structural Evaluation of Potent NKT-cell Agonists: Implications for Design of Novel Stimulatory Ligands

Natural Killer T (NKT) cells are a subset of T cells that are activated by CD1d-glycolipid complexes through a semi-invariant αβ T cell receptor (NKT TCR). Upon activation, NKT cells secrete regulatory cytokines that are implicated in T helper cell responses. α-Galactosylceramide (α-GalCer) is a pot...

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Detaylı Bibliyografya
Asıl Yazarlar: Schiefner, André, Fujio, Masakazu, Wu, Douglass, Wong, Chi-Huey, Wilson, Ian A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2009
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2792987/
https://ncbi.nlm.nih.gov/pubmed/19732779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.08.061
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