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Design of natural killer T cell activators: Structure and function of a microbial glycosphingolipid bound to mouse CD1d
Natural killer T (NKT) cells provide an innate-type immune response upon T cell receptor interaction with CD1d-presented antigens. We demonstrate through equilibrium tetramer binding and antigen presentation assays with Vα14i-positive NKT cell hybridomas that the Sphingomonas glycolipid α-galacturon...
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| Autores principales: | , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2006
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1449630/ https://ncbi.nlm.nih.gov/pubmed/16537470 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0600285103 |
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