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Sulfonyl fluorides as privileged warheads in chemical biology

Sulfonyl fluoride electrophiles have found significant utility as reactive probes in chemical biology and molecular pharmacology. As warheads they possess the right balance of biocompatibility (including aqueous stability) and protein reactivity. Their functionality is privileged in this regard as t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Chem Sci
Hauptverfasser: Narayanan, Arjun, Jones, Lyn H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Royal Society of Chemistry 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5489032/
https://ncbi.nlm.nih.gov/pubmed/28706662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5sc00408j
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