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Sulfonyl fluorides as privileged warheads in chemical biology

Sulfonyl fluoride electrophiles have found significant utility as reactive probes in chemical biology and molecular pharmacology. As warheads they possess the right balance of biocompatibility (including aqueous stability) and protein reactivity. Their functionality is privileged in this regard as t...

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Detaylı Bibliyografya
Yayımlandı:Chem Sci
Asıl Yazarlar: Narayanan, Arjun, Jones, Lyn H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Royal Society of Chemistry 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5489032/
https://ncbi.nlm.nih.gov/pubmed/28706662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5sc00408j
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