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Cucurbitacin B inhibits cell proliferation and induces apoptosis in human osteosarcoma cells via modulation of the JAK2/STAT3 and MAPK pathways

Osteosarcoma (OS) is the most commonly diagnosed tumor of the bones in children and young adults. Even with conventional therapies the 5-year survival rate is ~65% in patients with OS. Considering the side effects and aggressiveness of malignant bone tumors, research is focussing on multi-targeted s...

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Detalhes bibliográficos
Publicado no:Exp Ther Med
Main Authors: Zhang, Zhi-Ren, Gao, Ming-Xia, Yang, Kai
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5488743/
https://ncbi.nlm.nih.gov/pubmed/28673003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2017.4547
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