The Carbon monoxide releasing molecule ALF-186 mediates anti-inflammatory and neuroprotective effects via the soluble guanylate cyclase ß1 in rats’ retinal ganglion cells after ischemia and reperfusion injury

BACKGROUND: The endogenously produced gaseous molecule carbon monoxide is able to promote organ protection after ischemia-reperfusion injuries (IRI). The impact of carbon monoxide releasing molecules (CORM) regarding inflammation in neuronal tissues has not been studied in detail. In this investigat...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Ulbrich, Felix, Hagmann, Claus, Buerkle, Hartmut, Romao, Carlos C., Schallner, Nils, Goebel, Ulrich, Biermann, Julia
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5488359/
https://ncbi.nlm.nih.gov/pubmed/28655348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-017-0905-7
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