The CORM ALF-186 Mediates Anti-Apoptotic Signaling via an Activation of the p38 MAPK after Ischemia and Reperfusion Injury in Retinal Ganglion Cells

PURPOSE: Ischemia and reperfusion injury may induce apoptosis and lead to sustained tissue damage and loss of function, especially in neuronal organs. While carbon monoxide is known to exert protective effects after various harmful events, the mechanism of carbon monoxide releasing molecules in neur...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Ulbrich, Felix, Kaufmann, Kai B., Meske, Alexander, Lagrèze, Wolf A., Augustynik, Michael, Buerkle, Hartmut, Ramao, Carlos C., Biermann, Julia, Goebel, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5072679/
https://ncbi.nlm.nih.gov/pubmed/27764224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0165182
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