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Phenotype-based variation as a biomarker of sensitivity to molecularly targeted therapy in melanoma

Transcriptomic phenotypes defined for melanoma have been reported to correlate with sensitivity to various drugs. In this study, we aimed to define a minimal signature that could be used to distinguish melanoma sub-types in vitro, and to determine suitable drugs by which these sub-types can be targe...

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Detalhes bibliográficos
Publicado no:Medchemcomm
Main Authors: Senses, Kerem M., Ghasemi, Mehdi, Akbar, Muhammad W., Isbilen, Murat, Fallacara, Anna L., Frankenburg, Shoshana, Schenone, Silvia, Lotem, Michal, Botta, Maurizio, Gure, Ali O.
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5488266/
https://ncbi.nlm.nih.gov/pubmed/28670440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6md00466k
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