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Phenotype-based variation as a biomarker of sensitivity to molecularly targeted therapy in melanoma

Transcriptomic phenotypes defined for melanoma have been reported to correlate with sensitivity to various drugs. In this study, we aimed to define a minimal signature that could be used to distinguish melanoma sub-types in vitro, and to determine suitable drugs by which these sub-types can be targe...

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Détails bibliographiques
Publié dans:Medchemcomm
Auteurs principaux: Senses, Kerem M., Ghasemi, Mehdi, Akbar, Muhammad W., Isbilen, Murat, Fallacara, Anna L., Frankenburg, Shoshana, Schenone, Silvia, Lotem, Michal, Botta, Maurizio, Gure, Ali O.
Format: Artigo
Langue:Inglês
Publié: Royal Society of Chemistry 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5488266/
https://ncbi.nlm.nih.gov/pubmed/28670440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6md00466k
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