Adjuvant Autologous Melanoma Vaccine for Macroscopic Stage III Disease: Survival, Biomarkers, and Improved Response to CTLA-4 Blockade

Background. There is not yet an agreed adjuvant treatment for melanoma patients with American Joint Committee on Cancer stages III B and C. We report administration of an autologous melanoma vaccine to prevent disease recurrence. Patients and Methods. 126 patients received eight doses of irradiated...

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Veröffentlicht in:J Immunol Res
Hauptverfasser: Lotem, Michal, Merims, Sharon, Frank, Stephen, Hamburger, Tamar, Nissan, Aviram, Kadouri, Luna, Cohen, Jonathan, Straussman, Ravid, Eisenberg, Galit, Frankenburg, Shoshana, Carmon, Einat, Alaiyan, Bilal, Shneibaum, Shlomo, Ozge Ayyildiz, Zeynep, Isbilen, Murat, Mert Senses, Kerem, Ron, Ilan, Steinberg, Hanna, Smith, Yoav, Shiloni, Eitan, Gure, Ali Osmay, Peretz, Tamar
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2016
Schlagworte:
Clinical Study
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4887652/
https://ncbi.nlm.nih.gov/pubmed/27294163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/8121985
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