Arrhythmic effects of Epac‐mediated ryanodine receptor activation in Langendorff‐perfused murine hearts are associated with reduced conduction velocity

Recent papers have attributed arrhythmic substrate in murine RyR2‐P2328S hearts to reduced action potential (AP) conduction velocities (CV), reflecting acute functional inhibition and/or reduced expression of sodium channels. We explored for acute effects of direct exchange protein directly activate...

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Vydáno v:Clin Exp Pharmacol Physiol
Hlavní autoři: Li, Mengye, Hothi, Sandeep S, Salvage, Samantha C, Jeevaratnam, Kamalan, Grace, Andrew A, Huang, Christopher L‐H
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2017
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5488224/
https://ncbi.nlm.nih.gov/pubmed/28316073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/1440-1681.12751
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