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Non‐Enzymatic RNA Backbone Proofreading through Energy‐Dissipative Recycling
Non‐enzymatic oligomerization of activated ribonucleotides leads to ribonucleic acids that contain a mixture of 2′,5′‐ and 3′,5′‐linkages, and overcoming this backbone heterogeneity has long been considered a major limitation to the prebiotic emergence of RNA. Herein, we demonstrate non‐enzymatic ch...
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| Publicado no: | Angew Chem Int Ed Engl |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5488188/ https://ncbi.nlm.nih.gov/pubmed/28467695 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201703169 |
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