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Non‐Enzymatic RNA Backbone Proofreading through Energy‐Dissipative Recycling

Non‐enzymatic oligomerization of activated ribonucleotides leads to ribonucleic acids that contain a mixture of 2′,5′‐ and 3′,5′‐linkages, and overcoming this backbone heterogeneity has long been considered a major limitation to the prebiotic emergence of RNA. Herein, we demonstrate non‐enzymatic ch...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Angew Chem Int Ed Engl
Päätekijät: Mariani, Angelica, Sutherland, John D.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5488188/
https://ncbi.nlm.nih.gov/pubmed/28467695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201703169
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