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Identification of Antifungal H(+)-ATPase Inhibitors with Effect on Plasma Membrane Potential
The plasma membrane H(+)-ATPase (Pma1) is an essential fungal protein and a proposed target for new antifungal medications. The compounds in a small-molecule library containing ∼191,000 commercially available compounds were screened for their ability to inhibit Saccharomyces cerevisiae plasma membra...
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| Pubblicato in: | Antimicrob Agents Chemother |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5487681/ https://ncbi.nlm.nih.gov/pubmed/28438931 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00032-17 |
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