Treatment with Entinostat Heals Experimental Cholera by Affecting Physical and Chemical Barrier Functions of Intestinal Epithelia

We have shown previously that oral treatment with sodium butyrate or phenylbutyrate in an experimental model of shigellosis improves clinical outcomes and induces the expression of the antimicrobial peptide CAP-18 in the large intestinal epithelia. In a subsequent study, we found that entinostat, an...

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Publicat a:Antimicrob Agents Chemother
Autors principals: Sarker, Protim, Banik, Atanu, Stromberg, Roger, Gudmundsson, Gudmundur H., Raqib, Rubhana, Agerberth, Birgitta
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2017
Matèries:
Experimental Therapeutics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5487680/
https://ncbi.nlm.nih.gov/pubmed/28438947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02570-16
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