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Oral intake of phenylbutyrate with or without vitamin D(3) upregulates the cathelicidin LL-37 in human macrophages: a dose finding study for treatment of tuberculosis
BACKGROUND: We earlier showed that 4-phenylbutyrate (PB) can induce cathelicidin LL-37 expression synergistically with 1,25-dihydroxyvitamin D(3) in a lung epithelial cell line. We aimed to evaluate a therapeutic dose of PB alone or in combination with vitamin D(3) for induction of LL-37 expression...
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Principais autores: | , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3637063/ https://ncbi.nlm.nih.gov/pubmed/23590701 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2466-13-23 |
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