Phenylbutyrate Counteracts Shigella Mediated Downregulation of Cathelicidin in Rabbit Lung and Intestinal Epithelia: A Potential Therapeutic Strategy

BACKGROUND: Cathelicidins and defensins are endogenous antimicrobial peptides (AMPs) that are downregulated in the mucosal epithelia of the large intestine in shigellosis. Oral treatment of Shigella infected rabbits with sodium butyrate (NaB) reduces clinical severity and counteracts the downregulat...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Sarker, Protim, Ahmed, Sultan, Tiash, Snigdha, Rekha, Rokeya Sultana, Stromberg, Roger, Andersson, Jan, Bergman, Peter, Gudmundsson, Gudmundur H., Agerberth, Birgitta, Raqib, Rubhana
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2011
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3108617/
https://ncbi.nlm.nih.gov/pubmed/21673991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020637
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires