Selective Activation of Type II Interferon Signaling by Zika Virus NS5 Protein

Severe complications of Zika virus (ZIKV) infection might be caused by inflammation, but how ZIKV induces proinflammatory cytokines is not understood. In this study, we show opposite regulatory effects of the ZIKV NS5 protein on interferon (IFN) signaling. Whereas ZIKV and its NS5 protein were poten...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Virol
Main Authors: Chaudhary, Vidyanath, Yuen, Kit-San, Chan, Jasper Fuk-Woo, Chan, Ching-Ping, Wang, Pei-Hui, Cai, Jian-Piao, Zhang, Shuo, Liang, Mifang, Kok, Kin-Hang, Chan, Chi-Ping, Yuen, Kwok-Yung, Jin, Dong-Yan
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2017
Teme:
Pathogenesis and Immunity
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5487581/
https://ncbi.nlm.nih.gov/pubmed/28468880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00163-17
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