Selective Activation of Type II Interferon Signaling by Zika Virus NS5 Protein

Severe complications of Zika virus (ZIKV) infection might be caused by inflammation, but how ZIKV induces proinflammatory cytokines is not understood. In this study, we show opposite regulatory effects of the ZIKV NS5 protein on interferon (IFN) signaling. Whereas ZIKV and its NS5 protein were poten...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Chaudhary, Vidyanath, Yuen, Kit-San, Chan, Jasper Fuk-Woo, Chan, Ching-Ping, Wang, Pei-Hui, Cai, Jian-Piao, Zhang, Shuo, Liang, Mifang, Kok, Kin-Hang, Chan, Chi-Ping, Yuen, Kwok-Yung, Jin, Dong-Yan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5487581/
https://ncbi.nlm.nih.gov/pubmed/28468880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00163-17
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