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Mutations in the Transmembrane Domain and Cytoplasmic Tail of Hendra Virus Fusion Protein Disrupt Virus-Like-Particle Assembly

Hendra virus (HeV) is a zoonotic paramyxovirus that causes deadly illness in horses and humans. An intriguing feature of HeV is the utilization of endosomal protease for activation of the viral fusion protein (F). Here we investigated how endosomal F trafficking affects HeV assembly. We found that t...

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Библиографические подробности
Опубликовано в: :J Virol
Главные авторы: Cifuentes-Muñoz, Nicolás, Sun, Weina, Ray, Greeshma, Schmitt, Phuong Tieu, Webb, Stacy, Gibson, Kathleen, Dutch, Rebecca Ellis, Schmitt, Anthony P.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5487568/
https://ncbi.nlm.nih.gov/pubmed/28468881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00152-17
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