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Amyloid-β Impairs Vesicular Secretion in Neuronal and Astrocyte Peptidergic Transmission

Regulated secretion of neuropeptides and neurotrophic factors critically modulates function and plasticity of synapses and circuitries. It is believed that rising amyloid-β (Aβ) concentrations, synaptic dysfunction and network disorganization underlie early phases of Alzheimer’s disease (AD). Here,...

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Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: Plá, Virginia, Barranco, Neus, Pozas, Esther, Aguado, Fernando
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5487408/
https://ncbi.nlm.nih.gov/pubmed/28701919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00202
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