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Amyloid-β Impairs Vesicular Secretion in Neuronal and Astrocyte Peptidergic Transmission

Regulated secretion of neuropeptides and neurotrophic factors critically modulates function and plasticity of synapses and circuitries. It is believed that rising amyloid-β (Aβ) concentrations, synaptic dysfunction and network disorganization underlie early phases of Alzheimer’s disease (AD). Here,...

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Publicat a:Front Mol Neurosci
Autors principals: Plá, Virginia, Barranco, Neus, Pozas, Esther, Aguado, Fernando
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5487408/
https://ncbi.nlm.nih.gov/pubmed/28701919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00202
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