Downregulated USP3 mRNA functions as a competitive endogenous RNA of SMAD4 by sponging miR-224 and promotes metastasis in colorectal cancer

Increasing evidence shows that competitive endogenous RNAs (ceRNAs) can affect the expression of other transcripts by sequestering common microRNAs (miRNAs), and participate in tumourigenesis. As a potent tumour suppressor in colorectal cancer (CRC), SMAD4 is regulated by many miRNAs. However, the r...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Wang, Zaozao, Yang, Jie, Di, Jiabo, Cui, Ming, Xing, Jiadi, Wu, Fan, Wu, Wei, Yang, Hong, Zhang, Chenghai, Yao, Zhendan, Zhang, Nan, Jiang, Beihai, Su, Xiangqian
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2017
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5487320/
https://ncbi.nlm.nih.gov/pubmed/28655924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04368-3
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia