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Src42 binding activity regulates Drosophila RAF by a novel CNK-dependent derepression mechanism
Connector enhancer of KSR (CNK), an essential component of Drosophila receptor tyrosine kinase/mitogen-activated protein kinase pathways, regulates oppositely RAF function. This bimodal property depends on the N-terminal region of CNK, which integrates RAS activity to stimulate RAF and a bipartite e...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2005
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC548663/ https://ncbi.nlm.nih.gov/pubmed/15660123 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600558 |
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