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Bimodal regulation of RAF by CNK in Drosophila

Connector enhancer of KSR (CNK) is a multidomain-containing protein previously identified as a positive regulator of the RAS/MAPK pathway in Drosophila. Using transfection experiments and an RNAi-based rescue assay in Drosophila S2 cells, we demonstrate that CNK has antagonistic properties with resp...

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Detalhes bibliográficos
Main Authors: Douziech, Mélanie, Roy, François, Laberge, Gino, Lefrançois, Martin, Armengod, Anne-Valérie, Therrien, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC204489/
https://ncbi.nlm.nih.gov/pubmed/14517245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg506
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