The Intersection of NGF/TrkA Signaling and Amyloid Precursor Protein Processing in Alzheimer’s Disease Neuropathology

Dysfunction of nerve growth factor (NGF) and its high-affinity Tropomyosin receptor kinase A (TrkA) receptor has been suggested to contribute to the selective degeneration of basal forebrain cholinergic neurons (BFCN) associated with the progressive cognitive decline in Alzheimer's disease (AD)...

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Publicado en:Int J Mol Sci
Autores principales: Canu, Nadia, Amadoro, Giuseppina, Triaca, Viviana, Latina, Valentina, Sposato, Valentina, Corsetti, Veronica, Severini, Cinzia, Ciotti, Maria Teresa, Calissano, Pietro
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2017
Materias:
Review
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5486140/
https://ncbi.nlm.nih.gov/pubmed/28632177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18061319
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