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Perturbations in the Replication Program Contribute to Genomic Instability in Cancer
Cancer and genomic instability are highly impacted by the deoxyribonucleic acid (DNA) replication program. Inaccuracies in DNA replication lead to the increased acquisition of mutations and structural variations. These inaccuracies mainly stem from loss of DNA fidelity due to replication stress or d...
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| Опубликовано в: : | Int J Mol Sci |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
MDPI
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5485962/ https://ncbi.nlm.nih.gov/pubmed/28587102 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18061138 |
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