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Liver receptor homolog 1 contributes to intestinal tumor formation through effects on cell cycle and inflammation
Liver receptor homolog 1 (LRH-1) is an orphan nuclear receptor that synergizes with β-catenin/T cell factor 4 signaling to stimulate intestinal crypt cell renewal. We evaluated here the impact of haploinsufficiency of LRH-1 on intestinal tumorigenesis by using two independent mouse models of human c...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2005
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC548586/ https://ncbi.nlm.nih.gov/pubmed/15684064 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409756102 |
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