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Compromised Intestinal Lipid Absorption in Mice with a Liver-Specific Deficiency of Liver Receptor Homolog 1

Bile acids (BAs) are water-soluble end products from cholesterol metabolism and are essential for efficient absorption of dietary lipids. By using targeted somatic mutagenesis of the nuclear receptor liver receptor homolog 1 (LRH-1) in mouse hepatocytes, we demonstrate here that LRH-1 critically reg...

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Autors principals: Mataki, Chikage, Magnier, Benjamin C., Houten, Sander M., Annicotte, Jean-Sébastien, Argmann, Carmen, Thomas, Charles, Overmars, Henk, Kulik, Wim, Metzger, Daniel, Auwerx, Johan, Schoonjans, Kristina
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2169191/
https://ncbi.nlm.nih.gov/pubmed/17908794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00852-07
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