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In psychosis, cortical interneurons overexpress DNA-methyltransferase 1

Cortical DNA-methyltransferase 1 (DNMT1) is preferentially expressed in interneurons secreting GABA where it very likely contributes to promoter CpG island hypermethylation, thus causing a down-regulation of promoter functions. To consolidate and expand on previous findings that, in the cortex of sc...

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Библиографические подробности
Главные авторы: Veldic, Marin, Guidotti, Alessandro, Maloku, Ekrem, Davis, John M., Costa, Erminio
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2005
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC548582/
https://ncbi.nlm.nih.gov/pubmed/15684088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409665102
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