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In psychosis, cortical interneurons overexpress DNA-methyltransferase 1

Cortical DNA-methyltransferase 1 (DNMT1) is preferentially expressed in interneurons secreting GABA where it very likely contributes to promoter CpG island hypermethylation, thus causing a down-regulation of promoter functions. To consolidate and expand on previous findings that, in the cortex of sc...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Veldic, Marin, Guidotti, Alessandro, Maloku, Ekrem, Davis, John M., Costa, Erminio
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2005
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC548582/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15684088/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0409665102
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