Genomewide Association Study Identifies Novel Genetic Loci That Modify Antiplatelet Effects and Pharmacokinetics of Clopidogrel

Genetic variants in the pharmacokinetic (PK) mechanism are the main underlying factors affecting the antiplatelet response to clopidogrel. Using a genomewide association study (GWAS) to identify new genetic loci that modify antiplatelet effects in Chinese patients with coronary heart disease, we ide...

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Detalhes bibliográficos
Publicado no:Clin Pharmacol Ther
Main Authors: Zhong, W‐P, Wu, H, Chen, J‐Y, Li, X‐X, Lin, H‐M, Zhang, B, Zhang, Z‐W, Ma, D‐L, Sun, S, Li, H‐P, Mai, L‐P, He, G‐D, Wang, X‐P, Lei, H‐P, Zhou, H‐K, Tang, L, Liu, S‐W, Zhong, S‐L
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5485718/
https://ncbi.nlm.nih.gov/pubmed/27981573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.589
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