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Potentiation of the ligand-binding activity of integrin α3β1 via association with tetraspanin CD151
CD151, one of the tetraspanins, forms a stable complex with integrin α3β1, the major laminin receptor on the cell surface. We found that 8C3, an anti-CD151 mAb obtained by screening for reactivity with integrin α3β1–CD151 complexes, was capable of dissociating CD151 from integrin α3β1, thereby allow...
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| Główni autorzy: | , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
National Academy of Sciences
2005
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC548567/ https://ncbi.nlm.nih.gov/pubmed/15677332 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409493102 |
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