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Integrin-independent support of cancer drug resistance by tetraspanin CD151

Tetraspanin protein CD151 has typically been studied as binding partner and functional regulator of laminin-binding integrins. However, we show here that CD151 supports anti-cancer drug resistance independent of integrins. CD151 ablation sensitized multiple tumor cell types to several anti-cancer dr...

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Detalhes bibliográficos
Publicado no:Cell Mol Life Sci
Main Authors: Hwang, Soonyean, Takimoto, Takayuki, Hemler, Martin E.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6439156/
https://ncbi.nlm.nih.gov/pubmed/30778617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-019-03014-7
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