Potentiation of the ligand-binding activity of integrin α3β1 via association with tetraspanin CD151
CD151, one of the tetraspanins, forms a stable complex with integrin α3β1, the major laminin receptor on the cell surface. We found that 8C3, an anti-CD151 mAb obtained by screening for reactivity with integrin α3β1–CD151 complexes, was capable of dissociating CD151 from integrin α3β1, thereby allow...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2005
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC548567/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15677332/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0409493102 |
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