Influenza immunization elicits antibodies specific for an egg-adapted vaccine strain

For broad protection against infection by viruses such as influenza or HIV, vaccines should elicit antibodies that bind conserved viral epitopes, such as the receptor-binding site (RBS). RBS-directed antibodies have been described for both HIV(1–3) and influenza virus(4–8), and the design of immunog...

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Vydáno v:Nat Med
Hlavní autoři: Raymond, Donald D, Stewart, Shaun M, Lee, Jiwon, Ferdman, Jack, Bajic, Goran, Do, Khoi T, Ernandes, Michael J, Suphaphiphat, Pirada, Settembre, Ethan C, Dormitzer, Philip R, Giudice, Giuseppe Del, Finco, Oretta, Kang, Tae Hyun, Ippolito, Gregory C, Georgiou, George, Kepler, Thomas B, Haynes, Barton F, Moody, M Anthony, Liao, Hua-Xin, Schmidt, Aaron G, Harrison, Stephen C
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5485662/
https://ncbi.nlm.nih.gov/pubmed/27820604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.4223
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