Influenza immunization elicits antibodies specific for an egg-adapted vaccine strain

For broad protection against infection by viruses such as influenza or HIV, vaccines should elicit antibodies that bind conserved viral epitopes, such as the receptor-binding site (RBS). RBS-directed antibodies have been described for both HIV(1–3) and influenza virus(4–8), and the design of immunog...

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Udgivet i:Nat Med
Main Authors: Raymond, Donald D, Stewart, Shaun M, Lee, Jiwon, Ferdman, Jack, Bajic, Goran, Do, Khoi T, Ernandes, Michael J, Suphaphiphat, Pirada, Settembre, Ethan C, Dormitzer, Philip R, Giudice, Giuseppe Del, Finco, Oretta, Kang, Tae Hyun, Ippolito, Gregory C, Georgiou, George, Kepler, Thomas B, Haynes, Barton F, Moody, M Anthony, Liao, Hua-Xin, Schmidt, Aaron G, Harrison, Stephen C
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5485662/
https://ncbi.nlm.nih.gov/pubmed/27820604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.4223
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