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MicroRNA-142-3p and let-7g Negatively Regulates Augmented IL-6 Production in Neonatal Polymorphonuclear Leukocytes

Neonatal PMN are qualitatively impaired in functions, yet they frequently reveal augmented inflammatory reactions during sepsis. Here, we hypothesized that PMN from newborns produce more IL-6 than those from adults under LPS stimulation, in which transcriptional or posttranscriptional regulation is...

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Dades bibliogràfiques
Publicat a:Int J Biol Sci
Autors principals: Huang, Hsin-Chun, Yu, Hong-Ren, Hsu, Te-Yao, Chen, I-Lun, Huang, Hui-Chen, Chang, Jen-Chieh, Yang, Kuender D.
Format: Artigo
Idioma:Inglês
Publicat: Ivyspring International Publisher 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5485625/
https://ncbi.nlm.nih.gov/pubmed/28655995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.17030
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