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MicroRNA-142-3p and let-7g Negatively Regulates Augmented IL-6 Production in Neonatal Polymorphonuclear Leukocytes

Neonatal PMN are qualitatively impaired in functions, yet they frequently reveal augmented inflammatory reactions during sepsis. Here, we hypothesized that PMN from newborns produce more IL-6 than those from adults under LPS stimulation, in which transcriptional or posttranscriptional regulation is...

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Podrobná bibliografie
Vydáno v:Int J Biol Sci
Hlavní autoři: Huang, Hsin-Chun, Yu, Hong-Ren, Hsu, Te-Yao, Chen, I-Lun, Huang, Hui-Chen, Chang, Jen-Chieh, Yang, Kuender D.
Médium: Artigo
Jazyk:Inglês
Vydáno: Ivyspring International Publisher 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5485625/
https://ncbi.nlm.nih.gov/pubmed/28655995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.17030
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