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MicroRNA-142-3p and let-7g Negatively Regulates Augmented IL-6 Production in Neonatal Polymorphonuclear Leukocytes

Neonatal PMN are qualitatively impaired in functions, yet they frequently reveal augmented inflammatory reactions during sepsis. Here, we hypothesized that PMN from newborns produce more IL-6 than those from adults under LPS stimulation, in which transcriptional or posttranscriptional regulation is...

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Detalhes bibliográficos
Publicado no:Int J Biol Sci
Main Authors: Huang, Hsin-Chun, Yu, Hong-Ren, Hsu, Te-Yao, Chen, I-Lun, Huang, Hui-Chen, Chang, Jen-Chieh, Yang, Kuender D.
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5485625/
https://ncbi.nlm.nih.gov/pubmed/28655995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.17030
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