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AAV-mediated pancreatic overexpression of Igf1 counteracts progression to autoimmune diabetes in mice
OBJECTIVE: Type 1 diabetes is characterized by autoimmune destruction of β-cells leading to severe insulin deficiency. Although many improvements have been made in recent years, exogenous insulin therapy is still imperfect; new therapeutic approaches, focusing on preserving/expanding β-cell mass and...
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| 出版年: | Mol Metab |
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| 主要な著者: | , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Elsevier
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5485311/ https://ncbi.nlm.nih.gov/pubmed/28702323 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2017.05.007 |
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